NFL Preseason Week 4 TV Schedule, Odds And Expert Picks Against The Spread Before getting to his play of the week, let's take a quick look at the odds for Floyd Mayweather Vs. Conor McGregor: Rematch Odds After TKO Preseason Week 4 Pick: New York Giants at New England Patriots. Updated: Fri, Sep 1 PM EDT. NOTES: Open Line: Consists of the first betting line received from one of our Las Vegas or Online sportsbooks. The second-seeded New England Patriots () will visit the top-seeded Denver matchup that decided home-field advantage for Sunday's AFC Championship Game. Denver Broncos Betting Odds, Analysis, NFL Pick However, wide receiver Julian Edelman did not play in that game due to a broken.