The game, The Drive, The Comeback: The story behind the biggest win The Colts trailed the rival Patriots . Peyton Manning, quarterback (to NFL Films): Somebody said to me, . Finally, we called it when the Super Bowl was on the line. .. Colts quarterback Peyton Manning slaps hands with his. Largest victory, Patriots 42, Colts 3 (). Smallest victory, Colts 29, Patriots 28 () Colts 35, Patriots 34 (). Current win streak, Patriots, 7 wins ( present). The Colts – Patriots rivalry is a National Football League (NFL) rivalry between the Indianapolis .. The Colts drove to the Patriots ' 2-yard line in the final minute, only to be. Colts roster influenced by NFL village: Patriots influence is the biggest have had the biggest influence on the Indianapolis Colts roster. Missing: hands. NFL Week 16 early odds: Jets- Patriots opens as largest point spread in three years . On the other hand, the Vikings have done a good job of covering as The Colts are ATS and straight-up in games where they're. Colts roster influenced by NFL village: Patriots influence is the biggest have had the biggest influence on the Indianapolis Colts roster. Missing: hands. That is the largest point spread for an NFL game that does not involve Stadium to shake hands with Buffalo Bills head coach Dick Jauron, an.